This collection of photos contains both cancer and non-cancerous diseases of the oral environment which may be mistaken for malignancies. Some contain a brief patient history which may add insight to the actual diagnosis of the disease. As you review these images and their descriptions, you will be presented with what the referring doctor originally diagnosed and treated the patient for.


An elderly woman with advanced sun-induced degenerative alterations of face and lips. Presented with midline ulcerated mass.

Diagnosis: Squamous cell carcinoma, arising actinic cheilitis

Diagnosis: Squamous cell carcinoma, nodular/exothytic

64-year-old male with a long history of cigarette smoking presents with an asymmetrical nodular mass in the retromolar region.

Diagnosis: Squamous cell carcinoma, nodular/exothytic

Diagnosis: Erosive lichen planus

A 47-year-old male presents with a tender, well-defined ulceration of the left ventral tongue of 2 weeks duration.

Diagnosis: Erosive lichen planus

Diagnosis: Verrucous carcinoma

A 59-year-old female with a painless papillary mass of the left posterior mandibular alveolar ridge.

Diagnosis: Verrucous carcinoma

Diagnosis: Aspirin Burn

A 38-year-old a male presented with a white friable lesion of the maxillary gingiva which wiped off with a cotton swab, leaving a raw red base.

Diagnosis: Aspirin Burn

Diagnosis: Amalgam tattoo

A 31 year old female noticed a flat grey/black asymptomatic alteration in the anterior floor of her mouth, of unknown duration.

Diagnosis: Amalgam tattoo


The patient is a 64-year-old male with granular nodular partially ulcerated mass of the anterior mandibular gingiva.

Diagnosis: Squamous cell carcinoma


A bilaterally symmetrical ulcerative process noted by this 41-year-old female, present for several months. The patient is a non-smoker and uses no alcohol.

Diagnosis: Squamous cell carcinoma


Red and white surface alteration which is centrally indurated/firm was noted on routine examination in this 70-year-old male. The patient has a long time history of tobacco and alcohol abuse.

Diagnosis: Squamous cell carcinoma


On a routine examination of a 52-year-old female a well defined red velvety lesion of the lower-left ventral tongue was observed.

Clinical Diagnosis: Erythroplakia Microscopic | Diagnosis: Squamous cell carcinoma


Slightly elevated crater form and firm asymmetrical lesion were found on routine oral examination of the left lateral soft palette.

Diagnosis: Squamous cell carcinoma


A 69-year female presented with a sharply defined palatal ulceration.

Diagnosis: Squamous cell carcinoma


A 48-year-old female presents with a hard gingival swelling that on X-ray consisted of dense bone which was contiguous with the cortex.

Diagnosis: Osteoma


An 8-year-old child evaluated for the superficial, ulcerated, irregular lesion.

Diagnosis: Tramatic ulcer (facticious)


The patient has a white lesion with irregular margins on the left ventral tongue. At the inferior aspect, there is a prominent red patch of tissue.

Diagnosis: Carcinoma in situ


Blood-based, firm, asymptomatic nodule of long duration was noted along the right buccal mucosa during routine examination.

Diagnosis: Irritational fibroma


This 46-year-old female presents with irregular ulceration of the ventral lateral tongue, which is surrounded by leukoplakia.

Diagnosis Edge biopsy revealed squamous cell carcinoma


A flat, painless lesion of the mid-third of the tongue, showed sharply defined borders. This lesion was noted subsequent to a long course of antibiotic therapy.

Diagnosis: Median rhomboid glossitis